Tuberculosis
treatment in recent times should give permanent cure for TB infection which is
being caused by Mycobacterium
tuberculosis (Mtb). But the TB research was worried after knowing that
there is no prevention for reinfection. Here are the reasons why?
A recent publication revealed that the anti-TB
drugs changes the activity of gut microbiota and increases the susceptibility
to Mtb infection. Gut microbiota are crucial to keep us healthy; they involve
in food digestion, fights pathogenic microbes and protects our immune system.
Recent research has reported that chronic use of antibiotic (TB Drugs) leads to
disruption of this microbiome, which can in turn lead to dysregulation of the
immune system. It remains unclear, however, whether changes in the composition
of the microbes living in our gut have an influence on TB infection.
In an experimental
treatment for Tuberculosis with anti-TB drugs like isoniazid, rifampicin and
pyrazinamide for a period of eight weeks, they found that all of them significantly
changed the composition of the specimen gut microbiome, but the only specimen
treated with isoniazid combined with pyrazinamide showed an increase in
susceptibility to Mtb infection. This study can be completely understood by
knowing the Epidemiology
of TB, relationship of Lungs to gut microbiota.
To know about these details visit Mtb
reinfection and to share your scientific experiences on such conditions
take part in workshops and symposium carried on rare diseases (Tuberculosis is
said to be one of the rare diseases). We believe that Euro Epidemiology
congress will give some details on advanced research on these deadly and
dangerous diseases and controllable disorders for better human healthcare.
